Under whose possession is the property now?
Well to explain point wise:
He first gave a power of attorney to his nephew in 2002 because he is unmarried and had no time to maintain the building. In 2008, he again made a settlement deed in favor of his brother ( the nephew 's father) because some other person was harassing my friend then -
By the above the legal position is that the power of attorney given by your friend to his nephew in the year 2002 automatically stands revoked once the property of the POA was disposed by your friend himself by executing a settlement deed in favor of his brother in the year 2008. As sell as the property stands alienated from your friend to the beneficiary vide the referred settlement deed.
Now:
In the next year, in 2009, his brother again gave a power of attorney to my friend. By this power my friend donated this property to his own name. In 2010, my friend donated the same property to a charitable trust. In 2013, -
vide above statement, your friend's brother again executed a POA on the same property to his brother (i.e., your friend), however your friend misused the power by making a gift unto himself as a donor to a donee, where both the roles played by your friend himself. Subsequently the title holder, the your friend cum donee again executed a gift deed by gifting away the said property to a charitable trust, whereas, without knowing the legal status of the property your friend's brother executed a settlement deed in favor of his son on the same property in the year 2012 itself.
From the above it can be observed that though your friend's brother executed a POA in favor of your fiend, he did not specify in that deed that the agent can donate the property unto himself, therefore the donation or settlement deed by donor (the power agent will become donor on the basis of the power on his name) to himself in the capacity of donee is illegal and invalid in the eye of law hence his subsequent gift deed in the year 2013 also is invalid because the donor is not having marketable title to donate or gift the property to a donee.
Therefore the settlement made by your friend's brother in favor of his son can be held as valid and legal therefore if the property is not in their possession, they can file a suit for recovery of property and declaration of title.
Now you decide who can reclaim the property.