Best approach for mutual consent

I got married on 9th December 2018. My wife is an MBA and works at a reputed semi-govt college as an asst professor. Since marriage, we have had disagreements on almost everything. I do not have any siblings and my father passed away quite some back. It's only my mom, wife and me. She has not been taking care of my mother well and is not open to any kind of change/correction or is also not open to any discussion around my mom's preferences. Her family interferes in everything and have taken her away for almost 5-6 times to their house after marriage. At the moment as well, she is at her sister's place, I do not see a future with this person. I have not taken a rupee of dowry and the only ask was to take care of my mother. She does not encourage me discussing anything with my mother and wants to be independent/free. My mother's health has gone down badly post marriage and is really upset mentally due to all this. Please suggest best thing to do here and the best approach to be taken.